NLRC3 Restrains Responses to a T

The NOD-like receptor protein NLRC3 attenuates myeloid cell inflammatory responses. In this issue of Immunity, Uchimura et al. (2018) reveal additional T-cell-intrinsic functions for NLRC3 in restricting T cell metabolism, T helper 1 and T helper 17 cell responses, and antiviral and autoimmune respo...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2018-12, Vol.49 (6), p.989-991
Hauptverfasser:	Holley, Caroline L., Coll, Rebecca C., Schroder, Kate
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Autoimmune diseases Cytokines Disease Experiments Immunity Infections Inflammation Laboratories Lymphocytes Lymphocytes T Metabolism Proteins Studies T cell receptors Tumor necrosis factor-TNF Viral infections
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Beschreibung
Zusammenfassung:	The NOD-like receptor protein NLRC3 attenuates myeloid cell inflammatory responses. In this issue of Immunity, Uchimura et al. (2018) reveal additional T-cell-intrinsic functions for NLRC3 in restricting T cell metabolism, T helper 1 and T helper 17 cell responses, and antiviral and autoimmune responses. The NOD-like receptor protein NLRC3 attenuates myeloid cell inflammatory responses. In this issue of Immunity, Uchimura et al. (2018) reveal additional T-cell-intrinsic functions for NLRC3 in restricting T cell metabolism, T helper 1 and T helper 17 cell responses, and antiviral and autoimmune responses.
ISSN:	1074-7613 1097-4180
DOI:	10.1016/j.immuni.2018.12.003