Treatment-resistant depression: problematic illness or a problem in our approach?

Treatment-resistant depression: problematic illness or a problem in our approach?

Treatment-resistant depression is widely defined as non-response to two ‘adequate’ courses of treatment. However, the definitions of treatment and depression are inconsistent reflecting gaps in our understanding. We argue that a failure to respond is often the result of administering inappropriate t...

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Veröffentlicht in:British journal of psychiatry 2019-01, Vol.214 (1), p.1-3
Hauptverfasser: Malhi, Gin S., Das, Pritha, Mannie, Zola, Irwin, Lauren
Format: Artikel
Sprache:eng
Schlagworte:
Antidepressants
Antidepressive Agents - therapeutic use
Bipolar disorder
Depressive Disorder, Treatment-Resistant - diagnosis
Depressive Disorder, Treatment-Resistant - drug therapy
Editorial
Humans
Inappropriateness
Mental depression
Mental disorders
Patients
Personality disorders
Psychiatry
Severity of Illness Index
Treatment Failure
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Beschreibung
Zusammenfassung:Treatment-resistant depression is widely defined as non-response to two ‘adequate’ courses of treatment. However, the definitions of treatment and depression are inconsistent reflecting gaps in our understanding. We argue that a failure to respond is often the result of administering inappropriate treatment, which occurs principally because of paradigm failure.
ISSN:0007-1250
1472-1465
DOI:10.1192/bjp.2018.246