Dopamine and diet-induced obesity

Dopamine and diet-induced obesity

In 2010, Johnson and Kenny provided conclusive evidence that extended access to a Western-style diet promotes addictive-like behavior in rats by downregulating D 2 receptors while promoting obesity. This focused attention on the parallels between drug addiction and overeating and fueled a decade of...

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Veröffentlicht in:Nature neuroscience 2019-01, Vol.22 (1), p.1-2
Hauptverfasser: DiFeliceantonio, Alexandra G., Small, Dana M.
Format: Artikel
Sprache:eng
Schlagworte:
631/378/1488/393
631/378/1689/5
631/378/548/1964
Addiction
Animal Genetics and Genomics
Animals
Behavioral Sciences
Biological Techniques
Biomedical and Life Sciences
Biomedicine
Brain research
Cardiotonic agents
Diet
Dopamine
Dopamine D2 receptors
Drug addiction
Food Addiction
Hyperphagia
Medical schools
Neural circuitry
Neurobiology
Neurosciences
News & Views
news-and-views
Obesity
Phenols (Class of compounds)
Rats
Receptors
Receptors, Dopamine D2
Reward
Rodents
Universities and colleges
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Beschreibung
Zusammenfassung:In 2010, Johnson and Kenny provided conclusive evidence that extended access to a Western-style diet promotes addictive-like behavior in rats by downregulating D 2 receptors while promoting obesity. This focused attention on the parallels between drug addiction and overeating and fueled a decade of food addiction research.
ISSN:1097-6256
1546-1726
DOI:10.1038/s41593-018-0304-0