Unrelated donor vs HLA-haploidentical α/β T-cell– and B-cell–depleted HSCT in children with acute leukemia

Traditionally, hematopoietic stem cell transplantation (HSCT) from both HLA-matched related and unrelated donors (UD) has been used for treating children with acute leukemia (AL) in need of an allograft. Recently, HLA-haploidentical HSCT after αβ T-cell/B-cell depletion (αβhaplo-HSCT) was shown to b...

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Veröffentlicht in:	Blood 2018-12, Vol.132 (24), p.2594-2607
Hauptverfasser:	Bertaina, Alice, Zecca, Marco, Buldini, Barbara, Sacchi, Nicoletta, Algeri, Mattia, Saglio, Francesco, Perotti, Cesare, Gallina, Anna Maria, Bertaina, Valentina, Lanino, Edoardo, Prete, Arcangelo, Barberi, Walter, Tumino, Manuela, Favre, Claudio, Cesaro, Simone, Del Bufalo, Francesca, Ripaldi, Mimmo, Boghen, Stella, Casazza, Gabriella, Rabusin, Marco, Balduzzi, Adriana, Fagioli, Franca, Pagliara, Daria, Locatelli, Franco
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adolescent Allografts B-Lymphocytes Child Child, Preschool Chronic Disease Female Graft vs Host Disease - mortality Graft vs Host Disease - prevention & control Hematopoietic Stem Cell Transplantation Humans Infant Leukemia - mortality Leukemia - therapy Lymphocyte Depletion Male Receptors, Antigen, T-Cell, alpha-beta Retrospective Studies T-Lymphocytes Unrelated Donors
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