Skeletal fragility: an emerging complication of Ehlers–Danlos syndrome

Ehlers–Danlos syndrome (EDS) is an emerging cause of skeletal fragility. Mechanism of bone damage are probably multifactorial in line with the different skeletal phenotypes that can be found in clinical practice. A structured approach to clinical management of bone metabolic complication in EDS is p...

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Veröffentlicht in:	Endocrine 2019-02, Vol.63 (2), p.225-230
Hauptverfasser:	Formenti, Anna Maria, Doga, Mauro, Frara, Stefano, Ritelli, Marco, Colombi, Marina, Banfi, Giuseppe, Giustina, Andrea
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Bone Density - physiology Bone Diseases, Metabolic - diagnosis Bone Diseases, Metabolic - drug therapy Bone Diseases, Metabolic - etiology Bone strength Calcium Carbonate - therapeutic use Clinical Management of Endocrine Diseases Diabetes Ehlers-Danlos syndrome Ehlers-Danlos Syndrome - complications Ehlers-Danlos Syndrome - drug therapy Ehlers-Danlos Syndrome - metabolism Ehlers-Danlos Syndrome - pathology Endocrinology Female Follow-Up Studies Humanities and Social Sciences Humans Internal Medicine Lumbar Vertebrae - pathology Medicine Medicine & Public Health multidisciplinary Phenotypes Risk Factors Science Spinal Diseases - diagnosis Spinal Diseases - drug therapy Spinal Diseases - etiology Spinal Fractures - prevention & control Vitamin D - blood Vitamin D - therapeutic use Vitamin D Deficiency - complications Vitamin D Deficiency - diagnosis Vitamin D Deficiency - drug therapy
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Zusammenfassung:	Ehlers–Danlos syndrome (EDS) is an emerging cause of skeletal fragility. Mechanism of bone damage are probably multifactorial in line with the different skeletal phenotypes that can be found in clinical practice. A structured approach to clinical management of bone metabolic complication in EDS is proposed.
ISSN:	1355-008X 1559-0100
DOI:	10.1007/s12020-018-1822-y