Hepatitis E virus is not detected in association with neurological disorders among Brazilian children

Hepatitis E virus is not detected in association with neurological disorders among Brazilian children

Hepatitis E virus is increasingly being associated with idiopathic neurological disease. We tested 325 stool samples from Brazilian children presenting acute flaccid paralysis or Guillain-Barré syndrome using a broadly reactive and sensitive Reverse-transcription Polymerase chain reaction. Hepatitis...

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Veröffentlicht in:Microbes and infection 2019-04, Vol.21 (3-4), p.133-135
Hauptverfasser: Morgado, Lucas Nobrega, de Oliveira, Jaqueline Mendes, Pinto, Marcelo Alves, Burlandy, Fernanda Marcicano, E.da Silva, Edson, da Silva, Jaquelline Pereira, Vitral, Claudia Lamarca
Format: Artikel
Sprache:eng
Schlagworte:
Acute flaccid paralysis
Brazil
Brazil - epidemiology
Child
Feces - virology
Guillain-Barre Syndrome - epidemiology
Guillain-Barre Syndrome - virology
Guillain-barré syndrome
Hepatitis E
Hepatitis E virus - genetics
Hepatitis E virus - isolation & purification
Humans
Muscle Hypotonia - diagnosis
Muscle Hypotonia - epidemiology
Muscle Hypotonia - virology
Negative Results
Nervous System Diseases - epidemiology
Nervous System Diseases - etiology
Nervous System Diseases - virology
Paralysis - epidemiology
Paralysis - etiology
Paralysis - virology
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Zusammenfassung:Hepatitis E virus is increasingly being associated with idiopathic neurological disease. We tested 325 stool samples from Brazilian children presenting acute flaccid paralysis or Guillain-Barré syndrome using a broadly reactive and sensitive Reverse-transcription Polymerase chain reaction. Hepatitis E genome was not detected in any of the samples tested. Our results suggest that hepatitis E virus does not seem to be associated as the etiologic agent of acute flaccid paralysis and Guillain-Barré syndrome cases occurred in Brazilian children during the period of investigation (2010–2012).
ISSN:1286-4579
1769-714X
DOI:10.1016/j.micinf.2018.11.003