Conversion of aldimines to secondary amines using iron-catalysed hydrosilylation
Iron-catalyzed hydrosilylation of imines to amines using a well-defined iron complex is reported. This method employs relatively mild conditions, by reaction of imine, (EtO)3SiH in a 1 : 2 ratio in the presence of 1 mol% precatalyst ([BIAN]Fe(η6-toluene), 3, BIAN = bis(2,6-diisopropylaniline)acenaph...
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| Veröffentlicht in: | Organic & biomolecular chemistry 2018-12, Vol.16 (48), p.9368-9372 |
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| container_issue | 48 |
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| container_title | Organic & biomolecular chemistry |
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| creator | Saini, Anu Smith, Cecilia R Wekesa, Francis S Helms, Amanda K Findlater, Michael |
| description | Iron-catalyzed hydrosilylation of imines to amines using a well-defined iron complex is reported. This method employs relatively mild conditions, by reaction of imine, (EtO)3SiH in a 1 : 2 ratio in the presence of 1 mol% precatalyst ([BIAN]Fe(η6-toluene), 3, BIAN = bis(2,6-diisopropylaniline)acenaphthene) at 70 °C. A broad scope of imines was readily converted into the corresponding secondary amines without the need for precatalyst activators. |
| doi_str_mv | 10.1039/c8ob01262h |
| format | Article |
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| fulltext | fulltext |
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| ispartof | Organic & biomolecular chemistry, 2018-12, Vol.16 (48), p.9368-9372 |
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| language | eng |
| recordid | cdi_proquest_miscellaneous_2150533763 |
| source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Acenaphthene Amines Hydrosilylation Imines Iron Toluene |
| title | Conversion of aldimines to secondary amines using iron-catalysed hydrosilylation |
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