Molecular and epidemiologic investigation of a rhinovirus outbreak in a neonatal intensive care unit

We performed a molecular and epidemiologic study of a healthcare-associated rhinovirus outbreak to better understand transmission in neonatal intensive care settings. Sequencing of the 7 outbreak strains revealed 4 distinct clades, indicating multiple sources. A single clade infected 3 patients in a...

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Veröffentlicht in:	Infection control and hospital epidemiology 2019-02, Vol.40 (2), p.245-247
Hauptverfasser:	El Idrissi, Kenza Rahmouni, Isabel, Sandra, Carbonneau, Julie, Lafond, Martine, Quach, Caroline, Caya, Chelsea, Fontela, Patricia S, Beltempo, Marc, Boivin, Guy, Lefebvre, Marie-Astrid, Papenburg, Jesse
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Asymptomatic Cardiomyopathy Disease Outbreaks Enterovirus Infections - epidemiology Enterovirus Infections - virology Families & family life Humans Hygiene Infant, Newborn Infections Intensive care Intensive Care Units, Neonatal - statistics & numerical data Laboratories Newborn babies Nursing Ontario - epidemiology Outbreaks Patients Phylogenetics Rhinovirus - isolation & purification Software Ventilators
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Beschreibung
Zusammenfassung:	We performed a molecular and epidemiologic study of a healthcare-associated rhinovirus outbreak to better understand transmission in neonatal intensive care settings. Sequencing of the 7 outbreak strains revealed 4 distinct clades, indicating multiple sources. A single clade infected 3 patients in adjacent rooms, suggesting horizontal transmission. We observed 1 rhinovirus-associated death.
ISSN:	0899-823X 1559-6834
DOI:	10.1017/ice.2018.311