A High Ratio of Plasma: RBC Improves Survival in Massively Transfused Injured Children

A High Ratio of Plasma: RBC Improves Survival in Massively Transfused Injured Children

Massive transfusion protocols with balanced blood product ratios have been associated with improved outcomes in adult trauma. The impact on pediatric trauma is unclear. A retrospective review of the Pediatric Trauma Quality Improvement Program data set was performed using data from January 2015 to D...

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Veröffentlicht in:The Journal of surgical research 2019-01, Vol.233, p.213-220
Hauptverfasser: Cunningham, Megan E., Rosenfeld, Eric H., Zhu, Huirong, Naik-Mathuria, Bindi J., Russell, Robert T., Vogel, Adam M.
Format: Artikel
Sprache:eng
Schlagworte:
Blood product ratio
Damage control resuscitation
Hemorrhage
Massive transfusion
Pediatric
Trauma
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Zusammenfassung:Massive transfusion protocols with balanced blood product ratios have been associated with improved outcomes in adult trauma. The impact on pediatric trauma is unclear. A retrospective review of the Pediatric Trauma Quality Improvement Program data set was performed using data from January 2015 to December 2016. Trauma patient's ≤ 18 y of age, who received red blood cells (RBCs) and were massively transfused were included. Children with burns, dead on arrival, and nonsurvivable injuries were excluded. Outcome data and mortality were assessed based on low (
ISSN:0022-4804
1095-8673
DOI:10.1016/j.jss.2018.08.007