Autoclaving of Porous Silicon within a Hospital Environment: Potential Benefits and Problems

Autoclaving of Porous Silicon within a Hospital Environment: Potential Benefits and Problems

The microstructure and chemical composition of silicon surfaces subjected to standard sterilization protocols in hospital autoclaves has been examined. Both metallic contamination and structural changes can accompany porous Si hydrolysis. The in‐vitro incubation of bulk and porous Si discs with huma...

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Veröffentlicht in:Physica status solidi. A, Applied research Applied research, 2000-11, Vol.182 (1), p.555-560
Hauptverfasser: Jay, T., Canham, L.T., Heald, K., Reeves, C.L., Downing, R.
Format: Artikel
Sprache:eng
Schlagworte:
Autoclaves
Cells
Composition
Contamination
Crystal microstructure
Hospitals
Hydrolysis
Sterilization (cleaning)
Toxicity
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Zusammenfassung:The microstructure and chemical composition of silicon surfaces subjected to standard sterilization protocols in hospital autoclaves has been examined. Both metallic contamination and structural changes can accompany porous Si hydrolysis. The in‐vitro incubation of bulk and porous Si discs with human lymphocytes reveals potential sources of cytoxicity such as silane emission, and the supersaturation of media with eluted Si.
ISSN:0031-8965
1521-396X
DOI:10.1002/1521-396X(200011)182:1<555::AID-PSSA555>3.0.CO;2-G