Multilayer coatings using surface and bulk eroding polymers to create unique release profiles

Means of laminating CAP-P were sought, including mixed solvent systems, high polymer concentration, and water/solvent extraction. All methods focused on creating mechanically stable layers capable of transfer with sufficient residual solvent to plasticize layers for laminating. The surface eroding C...

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Veröffentlicht in:Annals of biomedical engineering 2000-01, Vol.28 (SUPPL. 1), p.S-14
Hauptverfasser: Raiche, Adrian, Puleo, David
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container_title Annals of biomedical engineering
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description Means of laminating CAP-P were sought, including mixed solvent systems, high polymer concentration, and water/solvent extraction. All methods focused on creating mechanically stable layers capable of transfer with sufficient residual solvent to plasticize layers for laminating. The surface eroding CAP-P system provided an excellent alternative to hPLGA when control of release was needed over a period of days.
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subjects Blending
Glass transition
Hydrophilicity
Molecular weight
Multilayers
Organic polymers
Plastic coatings
Polymer blends
Solvent extraction
Temperature
title Multilayer coatings using surface and bulk eroding polymers to create unique release profiles
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