Molecular Control of Bioactivity in Sol-Gel Glasses

Bioactive materials can be divided into: Class A bioactive glasses which exhibit rapid bonding to bone and soft connective tissue and are osteoproductive, and osteoconductive; and Class B bioactive ceramics, which bond slowly only to bone and are only osteoconductive. Bioactive sol-gel glasses compo...

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Veröffentlicht in:	Journal of sol-gel science and technology 1998-01, Vol.13 (1-3), p.245-250
Hauptverfasser:	Hench, Larry L, Wheeler, Donna L, Greenspan, David C
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Bioglass Biological activity Biomedical materials Bone Ceramic bonding Ceramic materials Connective tissues Glass Lime Phosphorus compounds Phosphorus pentoxide Porosity Silica Silicon dioxide Sol-gel processes Sol-gels Tissue culture
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Beschreibung
Zusammenfassung:	Bioactive materials can be divided into: Class A bioactive glasses which exhibit rapid bonding to bone and soft connective tissue and are osteoproductive, and osteoconductive; and Class B bioactive ceramics, which bond slowly only to bone and are only osteoconductive. Bioactive sol-gel glasses composed of SiO2-CaO-P2O5 have Class A behavior in vitro and in vivo and also resorb as they enhance the proliferation of new trabecular bone.
ISSN:	0928-0707 1573-4846
DOI:	10.1023/A:1008643303888