Electron spin resonance studies of some irradiated pharmaceuticals

Electron spin resonance studies of some irradiated pharmaceuticals

Five antibiotics belonging to the cephalosporins and penicillins groups have been irradiated: anhydrous ampicilline acid, amoxicilline acid trihydrate, cefuroxime sodium salt, cloxacilline sodium salt monohydrate and ceftazidime pentahydrate. ESR studies have been carried out, showing the influence...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Radiation physics and chemistry (Oxford, England : 1993) England : 1993), 2000-03, Vol.58 (1), p.69-76
Hauptverfasser: Gibella, M., Crucq, A-S., Tilquin, B., Stocker, P., Lesgards, G., Raffi, J.
Format: Artikel
Sprache:eng
Schlagworte:
Cephalosporin
Electron spin resonance
Electron spin resonance spectroscopy
Free radicals
Gamma irradiation
Gamma rays
Irradiation
Pharmaceuticals
Radiation effects
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Five antibiotics belonging to the cephalosporins and penicillins groups have been irradiated: anhydrous ampicilline acid, amoxicilline acid trihydrate, cefuroxime sodium salt, cloxacilline sodium salt monohydrate and ceftazidime pentahydrate. ESR studies have been carried out, showing the influence of irradiation and storage parameters on the nature and concentration of the free radicals trapped. These results may be used to detect an irradiation treatment on such pharmaceuticals.
ISSN:0969-806X
1879-0895
DOI:10.1016/S0969-806X(99)00353-9