Cell behavior on the alginate-coated PLLA/PLGA scaffolds

Cell behavior on the alginate-coated PLLA/PLGA scaffolds

Here, we investigated the effect of preparation temperature and alginate-coating on L929 fibroblast behavior on lyophilized microporous PLLA/PLGA (95:5, w/w) scaffolds. The lower freezing temperature used during lyophilization (−80 °C) resulted in smaller pores (around 50 μm) and higher compressive...

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Veröffentlicht in:International journal of biological macromolecules 2019-03, Vol.124, p.444-450
Hauptverfasser: Bahcecioglu, Gokhan, Hasirci, Nesrin, Hasirci, Vasif
Format: Artikel
Sprache:eng
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Zusammenfassung:Here, we investigated the effect of preparation temperature and alginate-coating on L929 fibroblast behavior on lyophilized microporous PLLA/PLGA (95:5, w/w) scaffolds. The lower freezing temperature used during lyophilization (−80 °C) resulted in smaller pores (around 50 μm) and higher compressive modulus (1500 kPa) than those prepared at the higher temperature (−20 °C) (pore size: 120 μm, compressive modulus: 600 kPa) (p 
ISSN:0141-8130
1879-0003
DOI:10.1016/j.ijbiomac.2018.11.169