Clinical utility of C-reactive protein, NON-HDL cholesterol and lipid ratios in patients with stroke

Stroke is a non-communicable disease of increasing socioeconomic importance in elderly populations. Just after the onsets of stroke in humans a range of inflammatory cells are activated. Evidence from observational studies indicates that high-sensitivity C-reactive protein (hsCRP), a peripheral marker of inflammation, is the strongest predictor of stroke. The various lipid ratios and nonhigh-density lipoprotein (non-HDL) cholesterol have not been as widely studied in association with stroke. The present study was therefore designed to evaluate the association of hsCRP, non-HDL cholesterol and lipid ratios with the scenario of risk of stroke. Hundred patients were recruited for the study, of which, fifty belongs to control and fifty were test group. Among the patients with complication, there was a significant elevation in the levels of hsCRP, non-HDL cholesterol and lipid ratios when compare with control. Detection of hsCRP, lipid ratios and non-HDL cholesterol are significant in patients with stroke and is important to stratify post stroke patients into risk groups.