Electrochemical cobalt-catalyzed C-H or N-H oxidation: a facile route to synthesis of substituted oxindoles

Two comparable protocols for the electrochemical cobalt-catalyzed C-H/N-H oxidation have been exploited for the synthesis of substituted oxindoles via radical pathways. The electrochemical cobalt-catalyzed system was demonstrated to be efficient and eco-friendly and avoided the use of stoichiometric...

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Veröffentlicht in:Organic & biomolecular chemistry 2018-11, Vol.16 (46), p.8917-8921
Hauptverfasser: Yu, Yue, Zheng, Peifeng, Wu, Yuanheng, Ye, Xiaoyi
Format: Artikel
Sprache:eng
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Zusammenfassung:Two comparable protocols for the electrochemical cobalt-catalyzed C-H/N-H oxidation have been exploited for the synthesis of substituted oxindoles via radical pathways. The electrochemical cobalt-catalyzed system was demonstrated to be efficient and eco-friendly and avoided the use of stoichiometric oxidants to afford the arylation or alkylation products in good yields at room temperature.
ISSN:1477-0520
1477-0539
DOI:10.1039/c8ob02485e