Status gelasticus associated with levetiracetam as add‐on treatment

ABSTRACT We report the case of a five‐year‐old girl, presenting with difficult‐to‐treat, symptomatic focal epilepsy, who developed status gelasticus following the introduction of levetiracetam as add‐on treatment to oxcarbazepine and diazepam. Gelastic seizures were documented by video‐EEG and were responsive to i.v. administration of diazepam. A possible causative role of levetiracetam is suggested. Specific susceptibility to some AEDs is also discussed, as this patient, at the age of four years, had presented an episode of non‐convulsive status epilepticus, following introduction of tiagabine, in association with vigabatrin and nitrazepam. [Published with video sequences] Content available: Video