Alginate microparticles loaded with basic fibroblast growth factor induce tissue coverage in a rat model of myelomeningocele

We sought to develop a minimally invasive intra-amniotic therapy for prenatal treatment of myelomeningocele (MMC) in an established rat model. Time-dated pregnant rats were gavage-fed retinoic acid to induce MMC. Groups received intraamniotic injections at E17.5 with alginate particles loaded with f...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of pediatric surgery 2019-01, Vol.54 (1), p.80-85
Hauptverfasser:	Farrelly, James S, Bianchi, Anthony H, Ricciardi, Adele S, Buzzelli, Gina L, Ahle, Samantha L, Freedman-Weiss, Mollie R, Luks, Valerie L, Saltzman, W Mark, Stitelman, David H
Format:	Artikel
Sprache:	eng
Schlagworte:	Alginate microparticles Fetal therapy Myelomeningocele Particle therapy Spina bifida
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!