Adherence Factors in Atypical Enteropathogenic Escherichia coli Strains Expressing the Localized Adherence-Like Pattern in HEp-2 Cells

Although atypical enteropathogenic Escherichia coli (aEPEC) strains are frequently implicated in childhood diarrhea in developing countries, not much is known about their adherence properties. The phenotypic and genotypic characterization of 29 aEPEC strains expressing the localized adherence-like p...

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Veröffentlicht in:	Journal of Clinical Microbiology 2010-01, Vol.48 (1), p.302-306
Hauptverfasser:	Scaletsky, Isabel C.A, Aranda, Katia R.S, Souza, Tamara B, Silva, Neusa P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesins, Escherichia coli - biosynthesis Adhesins, Escherichia coli - genetics Bacterial Typing Techniques Bacteriology Biological and medical sciences Cell Line Child Child, Preschool Enteropathogenic Escherichia coli - classification Enteropathogenic Escherichia coli - genetics Enteropathogenic Escherichia coli - isolation & purification Enteropathogenic Escherichia coli - pathogenicity Escherichia coli Escherichia coli Infections - microbiology Escherichia coli Proteins - biosynthesis Escherichia coli Proteins - genetics Fundamental and applied biological sciences. Psychology Hepatocytes - microbiology Humans Microbiology Miscellaneous Serotyping Virulence Factors - biosynthesis Virulence Factors - genetics
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Zusammenfassung:	Although atypical enteropathogenic Escherichia coli (aEPEC) strains are frequently implicated in childhood diarrhea in developing countries, not much is known about their adherence properties. The phenotypic and genotypic characterization of 29 aEPEC strains expressing the localized adherence-like pattern points toward the involvement of E. coli common pilus (ECP), intimins, and other known E. coli adhesins in this pattern.
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.01980-09