Nightly Variation in Sleep Apnea Severity as Atrial Fibrillation Risk

In this observational cohort study, we examined the relationship between simultaneous long-term day-by-day SDB and AF monitoring extracted from a deidentified home monitoring database of 191 patients with LivaNova Reply 200 (LivaNova, London, United Kingdom) or Kora 100 DR (Sorin CRM, Clamart, France) dual-chamber pacemakers implanted according to guideline-directed indications. A binary logistic generalized estimating equation (SPSS, version 24, IBM, Armonk, New York) was used to develop a prediction model for the dichotomous AF outcome (>5 min of cumulative mode switch per day) using the within-patient standardized (via quartiles) SDB severity data. [...]studies in well-characterized patient cohorts are needed to investigate the effect of concomitant risk factors on SDB day-to-day variability and whether the findings are applicable to the general AF population.