Seroprevalence of bovine intestinal schistosomosis in different agro- ecological zones of south India using excretory-secretory antigen based ELISA

•Bovine intestinal schistosomosis detected by indirect ELISA.•High prevalence in dairy animals of south India.•Indirect ELISA superior to copro PCR and microscopy.•First record of agro-ecological zone wise status. Intestinal schistosmosis caused by Schistosoma spindale and S. indicum is an important snail borne trematode infection that adversely affects the production and productivity of bovines in India. The present communication reports the high seroprevalence of infection among dairy cattle and buffaloes, under field conditions, utilizing a sensitive and specific excretory-secretory antigen based ELISA. Comparison of ELISA with copro-PCR, microscopy and post-mortem mesentery examination revealed the diagnostic superiority of ELISA. Seroprevalence of infection was mapped for the first time in India with special emphasis to agro- ecological zones. Anti-schistosome antibodies were detected in 34.96% of dairy cattle and buffaloes in the state with the evidence of significant influence of topography on the prevalence of infection. The study also highlighted the need to trace endemic pockets of infection in the country through efficient ante-mortem surveillance and to initiate anti-schistosome therapy prior to animal transport.