Minimally Invasive versus Abdominal Radical Hysterectomy for Cervical Cancer

In this prospective randomized trial, minimally invasive radical hysterectomy resulted in lower rates of disease-free survival and overall survival than open abdominal radical hysterectomy among women with early-stage cervical cancer. A prospective randomized trial and an epidemiologic study that us...

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Veröffentlicht in:	The New England journal of medicine 2018-11, Vol.379 (20), p.1895-1904
Hauptverfasser:	Ramirez, Pedro T, Frumovitz, Michael, Pareja, Rene, Lopez, Aldo, Vieira, Marcelo, Ribeiro, Reitan, Buda, Alessandro, Yan, Xiaojian, Shuzhong, Yao, Chetty, Naven, Isla, David, Tamura, Mariano, Zhu, Tao, Robledo, Kristy P, Gebski, Val, Asher, Rebecca, Behan, Vanessa, Nicklin, James L, Coleman, Robert L, Obermair, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Adenocarcinoma Adenocarcinoma - mortality Adenocarcinoma - surgery Adenosquamous Adult Cancer therapies Carcinoma, Adenosquamous - mortality Carcinoma, Adenosquamous - surgery Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - surgery Cervical cancer Cervix Chemotherapy Committees Disease-Free Survival Enrollments Female Humans Hypotheses Hysterectomy Hysterectomy - methods Laparoscopy Lymph Middle Aged Minimally invasive surgery Minimally Invasive Surgical Procedures Neoplasm Recurrence, Local Neoplasm Staging Oncology Patients Prospective Studies Radiation therapy Reproductive health Robotic surgery Robots Squamous cell carcinoma Surgeons Surgery Survival Rate Tomography Uterine Cervical Neoplasms - mortality Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - surgery
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Beschreibung
Zusammenfassung:	In this prospective randomized trial, minimally invasive radical hysterectomy resulted in lower rates of disease-free survival and overall survival than open abdominal radical hysterectomy among women with early-stage cervical cancer. A prospective randomized trial and an epidemiologic study that used large cancer databases (National Cancer Database and SEER) both showed that minimally invasive radical hysterectomy was associated with shorter survival in early cervical cancer than open abdominal radical hysterectomy.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa1806395