Effect of Supplemental Folic Acid in Pregnancy on Childhood Asthma: A Prospective Birth Cohort Study

This study aimed to investigate the effect of the timing, dose, and source of folate during pregnancy on childhood asthma by using data from an Australian prospective birth cohort study (n = 557) from 1998 to 2005. At 3.5 years and 5.5 years, 490 and 423 mothers and children participated in the stud...

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Veröffentlicht in:	American journal of epidemiology 2009-12, Vol.170 (12), p.1486-1493
Hauptverfasser:	Whitrow, Melissa J., Moore, Vivienne M., Rumbold, Alice R., Davies, Michael J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis. Health state Asthma Asthma - chemically induced Biological and medical sciences Breast Feeding Child Child, Preschool Chronic obstructive pulmonary disease, asthma Dietary Supplements - adverse effects Dose-Response Relationship, Drug Educational Status Epidemiology Female folic acid Folic Acid - adverse effects General aspects Humans Medical sciences Metabolic diseases methylation Pneumology Pregnancy Prenatal Exposure Delayed Effects - chemically induced preschool Preschool children Prospective Studies Public health. Hygiene Public health. Hygiene-occupational medicine Smoking Vitamin B
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Beschreibung
Zusammenfassung:	This study aimed to investigate the effect of the timing, dose, and source of folate during pregnancy on childhood asthma by using data from an Australian prospective birth cohort study (n = 557) from 1998 to 2005. At 3.5 years and 5.5 years, 490 and 423 mothers and children participated in the study, respectively. Maternal folate intake from diet and supplements was assessed by food frequency questionnaire in early (
ISSN:	0002-9262 1476-6256
DOI:	10.1093/aje/kwp315