The radioprotective efficacy of the rat acute-phase protein alpha2-macroglobulin on bone marrow cells

The aim of the present work was to evaluate the radioprotective effect on blood cells of alpha2M that, when administered 30 min before irradiation with 6.7 Gy (LD 50/30), provides 100% survival of experimental animals where in unprotected irradiated rats the said dose results in 50% lethality.

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Veröffentlicht in:	Genetika (Beograd) 2009, Vol.41 (1), p.29-39
Hauptverfasser:	Mihailovic, M, Vidakovic, M, Grdovic, N, Dinic, S, Uskokovic, A, Martinovic, S, Blagojevic, J., Institute for Biological Research Sinisa Stankovic, Belgrade (Serbia). Department of Molecular Biology
Format:	Artikel
Sprache:	eng
Schlagworte:	BONE MARROW GLOBULINAS GLOBULINE GLOBULINS http://www.fao.org/aos/agrovoc#c_11828 http://www.fao.org/aos/agrovoc#c_3279 http://www.fao.org/aos/agrovoc#c_3951 http://www.fao.org/aos/agrovoc#c_4870 http://www.fao.org/aos/agrovoc#c_6422 http://www.fao.org/aos/agrovoc#c_6464 http://www.fao.org/aos/agrovoc#c_998 IONIZING RADIATION IRRADIACION IRRADIATION MEDULA OSEA MITOSE MITOSIS MOELLE OSSEUSE RADIACION RADIACION IONIZANTE RADIATION RADIATION IONISANTE RAT RATA RATS
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Beschreibung
Zusammenfassung:	The aim of the present work was to evaluate the radioprotective effect on blood cells of alpha2M that, when administered 30 min before irradiation with 6.7 Gy (LD 50/30), provides 100% survival of experimental animals where in unprotected irradiated rats the said dose results in 50% lethality.
ISSN:	0534-0012 1820-6069
DOI:	10.2298/GENSR0901029M