SLAMF6 in health and disease: Implications for therapeutic targeting

•SLAMF6 is a cell surface receptor, expressed only on hematopoietic cells•SLAMF6 receptor can positively or negatively regulate immune responses•SLAMF6 is implicated in autoimmunity and cancer and this receptor can be targeted to help improve current treatment in various diseases.

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Veröffentlicht in:Clinical immunology (Orlando, Fla.) Fla.), 2019-07, Vol.204, p.3-13
Hauptverfasser: Yigit, Burcu, Wang, Ninghai, Herzog, Roland W., Terhorst, Cox
Format: Artikel
Sprache:eng
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Zusammenfassung:•SLAMF6 is a cell surface receptor, expressed only on hematopoietic cells•SLAMF6 receptor can positively or negatively regulate immune responses•SLAMF6 is implicated in autoimmunity and cancer and this receptor can be targeted to help improve current treatment in various diseases.
ISSN:1521-6616
1521-7035
DOI:10.1016/j.clim.2018.10.013