The association between the red cell distribution width and diabetic nephropathy in patients with type-2 diabetes mellitus

The association between the red cell distribution width and diabetic nephropathy in patients with type-2 diabetes mellitus

Background: Red cell distribution width (RDW) has been reported to be involved in metabolic syndrome and cardiovascular events. Patients with diabetic nephropathy (DN) are often found to be with high level of RDW. The aim of this study was to explore whether RDW was associated with DN severity and p...

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Veröffentlicht in:Renal failure 2018-11, Vol.40 (1), p.590-596
Hauptverfasser: Zhang, Junlin, Zhang, Rui, Wang, Yiting, Li, Hanyu, Han, Qianqian, Wu, Yucheng, Wang, Shanshan, Guo, Ruikun, Wang, Tingli, Li, Li, Liu, Fang
Format: Artikel
Sprache:eng
Schlagworte:
Biopsy
China
Clinical Study
Diabetes
Diabetes mellitus
Diabetes Mellitus, Type 2 - complications
Diabetic Nephropathies - blood
Diabetic Nephropathies - pathology
Diabetic Nephropathies - physiopathology
Diabetic nephropathy
Disease Progression
end-stage renal disease
Epidermal growth factor receptors
Erythrocyte Indices
Female
Glomerular Filtration Rate
Hemoglobin
Humans
Kaplan-Meier Estimate
Kidney Failure, Chronic - complications
Kidney Glomerulus - pathology
Male
Medical records
Metabolic syndrome
Middle Aged
Multivariate Analysis
Nephropathy
Patients
Proportional Hazards Models
Proteinuria
red cell distribution width
Risk Factors
Severity of Illness Index
type-2 diabetes mellitus
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Zusammenfassung:Background: Red cell distribution width (RDW) has been reported to be involved in metabolic syndrome and cardiovascular events. Patients with diabetic nephropathy (DN) are often found to be with high level of RDW. The aim of this study was to explore whether RDW was associated with DN severity and progression in patients with type-2 diabetes mellitus (T2DM). Methods: A total of 175 T2DM patients with biopsy-proven DN were enrolled. The baseline clinical and pathologic data of these patients was extracted from the medical records. The patients then were divided into two groups based on the median (13.6%) of RDW level; group 1:
ISSN:0886-022X
1525-6049
DOI:10.1080/0886022X.2018.1532906