Potent Activity of a Nucleoside Reverse Transcriptase Inhibitor, 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine, against Human Immunodeficiency Virus Type 1 Infection in a Model Using Human Peripheral Blood Mononuclear Cell-Transplanted NOD/SCID Janus Kinase 3 Knockout Mice

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2009-09, Vol.53 (9), p.3887-3893
Hauptverfasser:	HATTORI, Shinichiro, IDE, Kazuhiko, NAKATA, Hirotomo, HARADA, Hideki, SUZU, Shinya, ASHIDA, Noriyuki, KOHGO, Satoru, HAYAKAWA, Hiroyuki, MITSUYA, Hiroaki, OKADA, Seiji
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Biological and medical sciences Deoxyadenosines Deoxyadenosines - chemistry Deoxyadenosines - pharmacology Flow Cytometry HIV-1 HIV-1 - drug effects Human immunodeficiency virus Human immunodeficiency virus 1 Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Janus Kinase 3 Janus Kinase 3 - genetics Leukocytes, Mononuclear - transplantation Medical sciences Mice Mice, Inbred BALB C Mice, Inbred NOD Mice, Knockout Mice, SCID Molecular Structure Pharmacology. Drug treatments Reverse Transcriptase Inhibitors Reverse Transcriptase Inhibitors - chemistry Reverse Transcriptase Inhibitors - pharmacology Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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Zusammenfassung:	Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology. For an alternate route to AAC .asm.org, visit: AAC
ISSN:	0066-4804 1098-6596
DOI:	10.1128/aac.00270-09