Hyperthermic Intraperitoneal Chemotherapy After Extensive Cytoreductive Surgery in Patients with Primary Advanced Epithelial Ovarian Cancer: Interim Analysis of a Phase II Study

Background The objective of the current study was to evaluate the toxicities and treatment response of intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with advanced epithelial ovarian cancer. Methods Intraoperative HIPEC (cisplatin 75 mg/m 2 , 41.5°C, 90 min) was perform...

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Veröffentlicht in:	Annals of surgical oncology 2009-04, Vol.16 (4), p.993-1000
Hauptverfasser:	Lim, Myong Cheol, Kang, Sokbom, Choi, Jaeho, Song, Yong Jung, Park, Sohee, Seo, Sang-Soo, Park, Sang-Yoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Agents - administration & dosage Antineoplastic Agents - adverse effects Bridged-Ring Compounds - administration & dosage Bridged-Ring Compounds - adverse effects Chemotherapy, Adjuvant Cisplatin - administration & dosage Cisplatin - adverse effects Combined Modality Therapy Feasibility Studies Female Gynecologic Oncology Gynecologic Surgical Procedures - methods Humans Hyperthermia, Induced Infusions, Parenteral Intraoperative Period Medicine Medicine & Public Health Middle Aged Oncology Ovarian Neoplasms - drug therapy Ovarian Neoplasms - surgery Prospective Studies Surgery Surgical Oncology Taxoids - administration & dosage Taxoids - adverse effects Treatment Outcome
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Zusammenfassung:	Background The objective of the current study was to evaluate the toxicities and treatment response of intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with advanced epithelial ovarian cancer. Methods Intraoperative HIPEC (cisplatin 75 mg/m 2 , 41.5°C, 90 min) was performed in 30 patients with residual tumor of
ISSN:	1068-9265 1534-4681
DOI:	10.1245/s10434-008-0299-y