Longitudinal birth cohort study found that a significant proportion of children had abnormal metabolic profiles and insulin resistance at 6 years of age

Aim Metabolic syndrome represents a cluster of risk factors for cardiovascular disease, and we investigated whether otherwise healthy 6‐year‐olds showed metabolic alterations. Methods This study followed up a representative Swedish population‐based cohort of full‐term infants recruited on the matern...

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Veröffentlicht in:Acta Paediatrica 2019-03, Vol.108 (3), p.486-492
Hauptverfasser: Kjellberg, Emma, Roswall, Josefine, Bergman, Stefan, Almqvist‐Tangen, Gerd, Alm, Bernt, Dahlgren, Jovanna
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Sprache:eng
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Zusammenfassung:Aim Metabolic syndrome represents a cluster of risk factors for cardiovascular disease, and we investigated whether otherwise healthy 6‐year‐olds showed metabolic alterations. Methods This study followed up a representative Swedish population‐based cohort of full‐term infants recruited on the maternity ward at Hallands Hospital Halmstad, Sweden, from 2008 to 2011. They were examined at a mean of 6.6 years of age (range 6.5–6.9) using various measures for signs of metabolic syndrome. Results One key measure showed that 55 (26%) of the 212 children had one or more risk factors for metabolic syndrome requiring action. The 37 who were obese (3%) or overweight (14%) were significantly more likely to be insulin resistant than the normal weight group (28% versus 5%, p 
ISSN:0803-5253
1651-2227
DOI:10.1111/apa.14599