Identification of musculoskeletal infection with non-tuberculous mycobacterium using metagenomic sequencing

Identification of musculoskeletal infection with non-tuberculous mycobacterium using metagenomic sequencing

•We report four cases of refractory non-tuberculous mycobacterium musculoskeletal infection.•The report shows a novel use of metagenomic next-generation sequencing to detect pathogens.•All patients were cured through targeted antibiotic and surgeries.

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Bibliographische Detailangaben
Veröffentlicht in:The Journal of infection 2019-02, Vol.78 (2), p.158-169
Hauptverfasser: Huang, Zida, Zhang, Chongjing, Fang, Xinyu, Li, Wenbo, Zhang, Chaofan, Zhang, Wenming, Yang, Bin
Format: Artikel
Sprache:eng
Schlagworte:
Abscess
High-Throughput Nucleotide Sequencing
Humans
Metagenomic Next-Generation Sequencing
Musculoskeletal infection
Mycobacterium - genetics
Mycobacterium Infections
Non-tuberculous mycobacterium
Nontuberculous Mycobacteria
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Beschreibung
Zusammenfassung:•We report four cases of refractory non-tuberculous mycobacterium musculoskeletal infection.•The report shows a novel use of metagenomic next-generation sequencing to detect pathogens.•All patients were cured through targeted antibiotic and surgeries.
ISSN:0163-4453
1532-2742
DOI:10.1016/j.jinf.2018.10.002