Hyperpigmented Macule on the Palm and Diminished Sensation

A medical case of hyperpigmented macule on the palm and diminished sensation in a 25-year-old woman. She was diagnosed with tuberculoid leprosy with a single lesion and ulnar nerve involvement. Multidrug therapy including dapsone, clofazimine, and rifampin as the mainstay of treatment for leprosy du...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2018-11, Vol.320 (19), p.2029-2030
Hauptverfasser:	Awali, Reda, Chandrasekar, Pranatharthi H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Clofazimine Dapsone Dapsone - therapeutic use Diaminodiphenylsulfone Drug resistance Drug therapy Drug Therapy, Combination Female Hand - pathology Hand Dermatoses - diagnosis Hand Dermatoses - drug therapy Humans Hyperpigmentation - etiology Hypesthesia - etiology Leprostatic Agents - therapeutic use Leprosy Leprosy, Tuberculoid - complications Leprosy, Tuberculoid - diagnosis Leprosy, Tuberculoid - drug therapy Medical diagnosis Palm Rifampin Rifampin - therapeutic use Skin diseases
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Beschreibung
Zusammenfassung:	A medical case of hyperpigmented macule on the palm and diminished sensation in a 25-year-old woman. She was diagnosed with tuberculoid leprosy with a single lesion and ulnar nerve involvement. Multidrug therapy including dapsone, clofazimine, and rifampin as the mainstay of treatment for leprosy due to emerging drug resistance of dapsone.
ISSN:	0098-7484 1538-3598
DOI:	10.1001/jama.2018.14701