Normal pancreatic volume in adults is influenced by visceral fat, vertebral body width and age

Objectives The aim was to describe the pancreatic volume (PV) in a cohort of subjects with no prior history of pancreatic disease, and to explore the relationship between PV and conventional two-point measurements of the pancreas. Associations between PV, gender, age, abdominal body composition, and human height were explored as well. Methods CT scans from 204 trauma patients (20–80 years, 100 males) were evaluated. PV was measured with semi-automatic segmentation. Standardized two-point measurements of the pancreas were obtained together with L1 vertebral body size (a proxy for human height) and abdominal body composition. Associations between PV and the other parameters were explored using uni- and multivariate linear regression. Results The mean PV was 77.9 ± 21.7(SD) cm 3 with an interindividual variability from 18.8 to 139.8 cm 3 . The transversal diameter of the pancreatic head showed the strongest correlation to PV ( r = 0.500, p