Towards therapeutic base editing

Base editors function in mouse fetuses and in the livers of adult mice to treat a genetic disorder.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature medicine 2018-10, Vol.24 (10), p.1493-1495
Hauptverfasser:	Seo, Huiyun, Kim, Jin-Soo
Format:	Artikel
Sprache:	eng
Schlagworte:	692/420/2489/201 Animals Antigens Biomedical and Life Sciences Biomedicine Cancer Cancer Research Care and treatment CRISPR CRISPR-Cas Systems Editors Embryos Enzymes Fetuses Gene Editing Gene mutation Gene therapy Genes Genetic disorders Genomics Guanine Health aspects Infectious Diseases Leukemia Ligands Liver Diseases - genetics Lymphocytes Medicine Metabolic Diseases Metabolism Methods Mice Molecular Medicine Mutation Neurosciences News & Views news-and-views Purines Pyrimidines RNA Tumors Universities and colleges
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Beschreibung
Zusammenfassung:	Base editors function in mouse fetuses and in the livers of adult mice to treat a genetic disorder.
ISSN:	1078-8956 1546-170X
DOI:	10.1038/s41591-018-0215-3