Towards therapeutic base editing

Towards therapeutic base editing

Base editors function in mouse fetuses and in the livers of adult mice to treat a genetic disorder.

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Bibliographische Detailangaben
Veröffentlicht in:Nature medicine 2018-10, Vol.24 (10), p.1493-1495
Hauptverfasser: Seo, Huiyun, Kim, Jin-Soo
Format: Artikel
Sprache:eng
Schlagworte:
692/420/2489/201
Animals
Antigens
Biomedical and Life Sciences
Biomedicine
Cancer
Cancer Research
Care and treatment
CRISPR
CRISPR-Cas Systems
Editors
Embryos
Enzymes
Fetuses
Gene Editing
Gene mutation
Gene therapy
Genes
Genetic disorders
Genomics
Guanine
Health aspects
Infectious Diseases
Leukemia
Ligands
Liver Diseases - genetics
Lymphocytes
Medicine
Metabolic Diseases
Metabolism
Methods
Mice
Molecular Medicine
Mutation
Neurosciences
News & Views
news-and-views
Purines
Pyrimidines
RNA
Tumors
Universities and colleges
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Beschreibung
Zusammenfassung:Base editors function in mouse fetuses and in the livers of adult mice to treat a genetic disorder.
ISSN:1078-8956
1546-170X
DOI:10.1038/s41591-018-0215-3