Randomized trial of the efficacy of intravaginal ulinastatin administration for the prevention of preterm birth in women with a singleton pregnancy and both cervical shortening and inflammation of lower genital tract

Randomized trial of the efficacy of intravaginal ulinastatin administration for the prevention of preterm birth in women with a singleton pregnancy and both cervical shortening and inflammation of lower genital tract

Aim To assess the preventive effect on preterm birth of intravaginal ulinastatin (urinary trypsin inhibitor; UTI) administration during the mid‐trimester in women with singleton pregnancy and both cervical shortening and lower genital infections. Methods Pregnant women with a short cervical length ...

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Veröffentlicht in:The journal of obstetrics and gynaecology research 2019-01, Vol.45 (1), p.86-95
Hauptverfasser: Otsuki, Katsufumi, Kawabata, Ikuno, Matsuda, Yoshio, Nakai, Akihito, Shinozuka, Norio, Makino, Yasuo, Kamei, Yoshimasa, Iwashita, Mitsutoshi, Okai, Takashi
Format: Artikel
Sprache:eng
Schlagworte:
Administration, Intravaginal
Adult
Birth
Cervical Length Measurement
cervical shortening
Cervix Uteri - diagnostic imaging
Cervix Uteri - pathology
Chorioamnionitis
Female
Genital tract
Gestation
Glycoproteins - administration & dosage
Glycoproteins - pharmacology
Health risk assessment
Human papillomavirus
Humans
Infections
Inflammation
intravaginal ulinastatin administration
Outcome Assessment (Health Care)
Patients
Pregnancy
Premature birth
Premature Birth - etiology
Premature Birth - prevention & control
preterm birth
randomized controlled trial
Trypsin
Trypsin Inhibitors - administration & dosage
Trypsin Inhibitors - pharmacology
Uterine Cervicitis - complications
Vagina
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Beschreibung
Zusammenfassung:Aim To assess the preventive effect on preterm birth of intravaginal ulinastatin (urinary trypsin inhibitor; UTI) administration during the mid‐trimester in women with singleton pregnancy and both cervical shortening and lower genital infections. Methods Pregnant women with a short cervical length 
ISSN:1341-8076
1447-0756
DOI:10.1111/jog.13796