Gait Characteristics of Children and Youth With Chemotherapy Induced Peripheral Neuropathy Following Treatment for Acute Lymphoblastic Leukemia

Highlights • Neuropathy is a possible sequelae of leukemia treatment which can impact walking. • Gait of youth with neuropathy is described using 3D motion analysis and EMG. • Participants demonstrated a variety gait deviations and compensatory mechanisms. • Clinical decisions should be based on ind...

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Veröffentlicht in:	Gait & posture 2017-10, Vol.58 (NA), p.139-145
Hauptverfasser:	Wright, Marilyn J, Twose, Donna M, Gorter, Jan Willem
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - adverse effects Antineoplastic Agents, Phytogenic - therapeutic use Biomechanical Phenomena Child Electromyography Female Gait Gait - physiology Gait Disorders, Neurologic - diagnosis Gait Disorders, Neurologic - etiology Gait Disorders, Neurologic - physiopathology Humans Imaging, Three-Dimensional Leukemia Male Muscle, Skeletal - physiopathology Neuropathy Orthopedics Peripheral Nervous System Diseases - chemically induced Peripheral Nervous System Diseases - complications Peripheral Nervous System Diseases - physiopathology Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Vincristine - adverse effects Vincristine - therapeutic use Walking - physiology
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Beschreibung
Zusammenfassung:	Highlights • Neuropathy is a possible sequelae of leukemia treatment which can impact walking. • Gait of youth with neuropathy is described using 3D motion analysis and EMG. • Participants demonstrated a variety gait deviations and compensatory mechanisms. • Clinical decisions should be based on individual impairments and gait abnormalities.
ISSN:	0966-6362 1879-2219
DOI:	10.1016/j.gaitpost.2017.05.004