Ondansetron or promethazine: Which one is better for the treatment of acute peripheral vertigo?

Vertigo is a common annoying complaint needing emergent treatment. There are various treatment options for this condition with different outcomes and side effects. Assessment and comparison of the effectiveness of Ondansetron and Promethazine in the treatment of acute peripheral vertigo. This clinic...

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Veröffentlicht in:American journal of otolaryngology 2019-01, Vol.40 (1), p.10-15
Hauptverfasser: Saberi, Alia, Pourshafie, Seyed Hashem, Kazemnejad-Leili, Ehsan, Nemati, Shadman, Sutohian, Sara, Sayad-Fathi, Sara
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Sprache:eng
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Zusammenfassung:Vertigo is a common annoying complaint needing emergent treatment. There are various treatment options for this condition with different outcomes and side effects. Assessment and comparison of the effectiveness of Ondansetron and Promethazine in the treatment of acute peripheral vertigo. This clinical trial was conducted in an academic hospital in the north of Iran in 2017. A total of 170 eligible patients were randomly allocated to groups A: received intramuscular (IM) promethazine; and B: received intravenous (IV) Ondansetron, using quadripartite blocks. The severity of vertigo, nausea, blood pressure, heart rate, side-effects, need for re-administration, and the time to become asymptomatic were assessed before the injections, 30 min after and 2 h after the injections. Excellent improvement in vertigo occurred in both groups (P 
ISSN:0196-0709
1532-818X
DOI:10.1016/j.amjoto.2018.09.010