Editorial commentary: Epithelial-to-Mesenchymal transition and G protein-coupled receptors: A novel possibility for cardiac regeneration?
Various metabolic disorders like obesity, diabetes and high blood pressure sequentially cause numerous CVDs like hypertension, cardiomyopathies, cardiac arrest, cardiac valve calcification and arrhythmias among others [1]. In a different study, selective serotonin reuptake inhibitor (SSRI) Fluoxetin...
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| Veröffentlicht in: | Trends in cardiovascular medicine 2019-05, Vol.29 (4), p.205-206 |
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| container_title | Trends in cardiovascular medicine |
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| creator | Borlepawar, Ankush Frey, Norbert Frank, Derk |
| description | Various metabolic disorders like obesity, diabetes and high blood pressure sequentially cause numerous CVDs like hypertension, cardiomyopathies, cardiac arrest, cardiac valve calcification and arrhythmias among others [1]. In a different study, selective serotonin reuptake inhibitor (SSRI) Fluoxetine lead to dilated cardiomyopathy in rodents and cardiac malfunctions in humans, putting question mark over prenatal SSRI treatment [17]. [...]this review emphasizes the very central mechanism of embryonic and disease growth modulation through GPCRs, which can have tremendous clinical potential in cardiovascular disease managements. |
| doi_str_mv | 10.1016/j.tcm.2018.09.008 |
| format | Article |
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In a different study, selective serotonin reuptake inhibitor (SSRI) Fluoxetine lead to dilated cardiomyopathy in rodents and cardiac malfunctions in humans, putting question mark over prenatal SSRI treatment [17]. 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In a different study, selective serotonin reuptake inhibitor (SSRI) Fluoxetine lead to dilated cardiomyopathy in rodents and cardiac malfunctions in humans, putting question mark over prenatal SSRI treatment [17]. 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| ispartof | Trends in cardiovascular medicine, 2019-05, Vol.29 (4), p.205-206 |
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| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Blood pressure Calcification (ectopic) Cardiomyopathy Cardiovascular diseases Congenital diseases Defects Diabetes mellitus Dilated cardiomyopathy Disease Embryos Epigenetics Epithelial-Mesenchymal Transition Fluoxetine G protein-coupled receptors Gene expression Heart Heart attacks Humans Hypertension Ligands Mesenchyme Mortality Receptors, G-Protein-Coupled Regeneration Serotonin Serotonin uptake inhibitors Transcription factors |
| title | Editorial commentary: Epithelial-to-Mesenchymal transition and G protein-coupled receptors: A novel possibility for cardiac regeneration? |
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