Vitamin D supplementation does not improve plasma thiol/disulfide homeostasis

Background Impairment of thiol/disulfide homeostasis, as well as vitamin D deficiency, are responsible for the pathophysiology of many acute and chronic diseases. This study examined the relationship between thiol/disulfide homeostasis and vitamin D level and supplementation. Methods A total of 203...

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Veröffentlicht in:	Pediatrics international 2018-11, Vol.60 (11), p.1008-1013
Hauptverfasser:	Mertoglu, Cuma, Siranli, Gulsah, Topal, Ismail, Gok, Gamze, Erel, Ozcan
Format:	Artikel
Sprache:	eng
Schlagworte:	25-Hydroxyvitamin D Adolescent Biomarkers - blood Child Child, Preschool Children Chronic illnesses Dietary Supplements Disulfides - blood Female healthy child Homeostasis Homeostasis - drug effects Humans Impairment Infant Infant, Newborn Male Oxidation Oxidative stress Pediatrics Sulfhydryl Compounds - blood Supplements thiol/disulfide homeostasis Treatment Outcome Vitamin D Vitamin D - pharmacology Vitamin D - therapeutic use Vitamin D Deficiency - blood Vitamin D Deficiency - drug therapy Vitamin D Deficiency - physiopathology Vitamin deficiency Vitamins - pharmacology Vitamins - therapeutic use
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Zusammenfassung:	Background Impairment of thiol/disulfide homeostasis, as well as vitamin D deficiency, are responsible for the pathophysiology of many acute and chronic diseases. This study examined the relationship between thiol/disulfide homeostasis and vitamin D level and supplementation. Methods A total of 203 healthy children were included in the study. The participants were divided into four groups according to 25‐hydroxyvitamin D (25(OH)D) level: group 1, severe deficiency (
ISSN:	1328-8067 1442-200X
DOI:	10.1111/ped.13705