Estimation of Disease Prevalence from a Screening Program

The estimation problem of disease prevalence from a screening program is considered. Due to the imperfect nature of a screening test, the estimate should be adjusted based upon the sensitivity and the specificity of the screening test. Several approximate methods of constructing the confidence inter...

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Veröffentlicht in:	Biometrical journal 2001-11, Vol.43 (7), p.835-843
Hauptverfasser:	Shin, Hyun Chul, Kim, Byung Chun, Park, Sang Gue
Format:	Artikel
Sprache:	eng
Schlagworte:	Disease prevalence Exact sciences and technology Mathematics Parametric inference Probability and statistics Relative risk Sciences and techniques of general use Score method Screening program Sensitivity Specificity Statistics
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Beschreibung
Zusammenfassung:	The estimation problem of disease prevalence from a screening program is considered. Due to the imperfect nature of a screening test, the estimate should be adjusted based upon the sensitivity and the specificity of the screening test. Several approximate methods of constructing the confidence interval of prevalence are given and the score method is proposed in detail. A simulation study is also presented and discussed.
ISSN:	0323-3847 1521-4036
DOI:	10.1002/1521-4036(200111)43:7<835::AID-BIMJ835>3.0.CO;2-W