Synthesis and its DNA Detecting Ability of Fluorescent Modified .BETA.-cyclodextrins having Long Chain Connected by pyrene Unit

Synthesis and its DNA Detecting Ability of Fluorescent Modified .BETA.-cyclodextrins having Long Chain Connected by pyrene Unit

Two kinds of pyrene modified beta -cyclodextrins, which are different in linker parts to bind between beta -cyclodextrin and pyrene unit, were synthesized. Those derivatives show different behavior for single and double strands of DNA, where short linker derivative shows no interaction for DNA, but...

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Veröffentlicht in:INTERNATIONAL JOURNAL OF THE SOCIETY OF MATERIALS ENGINEERING FOR RESOURCES 2009, Vol.16 (1_2), p.16-21
Hauptverfasser: Matsumura, Noriaki, Kagaya, Masami, Kondo, Yoshihiko, Akagami, Youichi, Hamada, Fumio
Format: Artikel
Sprache:eng
Schlagworte:
Chains
Deoxyribonucleic acid
Derivatives
Fluorescence
Materials engineering
Pyrenes
Strands
Synthesis
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Beschreibung
Zusammenfassung:Two kinds of pyrene modified beta -cyclodextrins, which are different in linker parts to bind between beta -cyclodextrin and pyrene unit, were synthesized. Those derivatives show different behavior for single and double strands of DNA, where short linker derivative shows no interaction for DNA, but longer linker derivative indicates there are something interaction for DNA by intercalating of pyrene unit.
ISSN:1347-9725
1884-6629
DOI:10.5188/ijsmer.16.16