Effect of Ethanol Extract of Cansjera rheedii J. Gmelin (Opiliaceae) on Hepatotoxicity
The hepatoprotective activity of ethanol (95%) extract of (250 mg kg super(-1)) Cansjera rheedii J. Gmelin whole plant was evaluated against paracetamol induced hepatotoxicity by evaluating biochemical parameters such as Serum Glutamate Pyruvate Transaminase (SGPT), Serum Glutamate Oxaloacetate Tran...
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| Veröffentlicht in: | Journal of pharmacology & toxicology 2008, Vol.3 (2), p.158-162 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | The hepatoprotective activity of ethanol (95%) extract of (250 mg kg super(-1)) Cansjera rheedii J. Gmelin whole plant was evaluated against paracetamol induced hepatotoxicity by evaluating biochemical parameters such as Serum Glutamate Pyruvate Transaminase (SGPT), Serum Glutamate Oxaloacetate Transaminase (SGOT), Alkaline Phosphatase (ALP), Total bilirubin, Total Protein and Gamma Glutamate Transpeptidase (GGTP). A 10% of liver homogenate was used for estimation of enzyme such as Superoxide Dismutase (SOD), Glutathione S-Transferase (GST), Lipid Peroxidase (LPO) and Glutathione Peroxidase (GPx) for antioxidant study. Treatment of rats with ethanol extract significantly (p |
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| ISSN: | 1816-496X |
| DOI: | 10.3923/jpt.2008.158.162 |