Chronology of the HIV-1 CRF07_BC expansion in East Asia

The HIV-1 epidemic among injecting drug users (IDU) in Taiwan is caused primarily by CRF07_BC infections. Evolutionary analyses, which utilize outgroup reference strains from northwestern China (Xinjiang), reveal that CRF07_BC was introduced into southern Taiwan in 1998-2001 and spread to central-no...

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Veröffentlicht in:	AIDS (London) 2008-01, Vol.22 (1), p.156-158
Hauptverfasser:	KOK KENG TEE, PYBUS, Oliver G, HUANAN LIAO, UENISHI, Rie, HASE, Saiki, KAMARULZAMAN, Adeeba, LI, Xiao-Jie, TAKEBE, Yutaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences China - epidemiology Disease Outbreaks env Gene Products, Human Immunodeficiency Virus - genetics Genes, Viral - genetics HIV Infections - epidemiology HIV-1 - genetics Human immunodeficiency virus 1 Human viral diseases Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Medical sciences Phylogeny Substance Abuse, Intravenous Taiwan - epidemiology Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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Zusammenfassung:	The HIV-1 epidemic among injecting drug users (IDU) in Taiwan is caused primarily by CRF07_BC infections. Evolutionary analyses, which utilize outgroup reference strains from northwestern China (Xinjiang), reveal that CRF07_BC was introduced into southern Taiwan in 1998-2001 and spread to central-northern Taiwan in 2001-2003, causing the largest HIV/AIDS epidemic in Taiwan. The separate introduction of CRF07_BC into Xinjiang occurred in 1992-1995. This study illustrates the temporal dynamics of CRF07_BC spread among IDU across east Asia.
ISSN:	0269-9370 1473-5571
DOI:	10.1097/QAD.0b013e3282f2d77a