Progressive multifocal leukoencephalopathy: prolonged survival in patients treated with protease inhibitors and cidofovir : a case series

The prognosis of patients with progressive multifocal leukoencephalopathy (PML) has been reported to be poor even in the HAART era, with median survivals of 131-646 days in previous studies. We report a much longer median survival in all patients with confirmed PML presenting to our unit between 199...

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Veröffentlicht in:	AIDS (London) 2006-03, Vol.20 (5), p.791-793
Hauptverfasser:	GARVEY, Lucy, THOMSON, Emma C, TAYLOR, Graham P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anti-HIV Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences Brain - pathology Cytosine - analogs & derivatives Cytosine - therapeutic use Female HIV Protease Inhibitors - therapeutic use Human viral diseases Humans Infectious diseases Leukoencephalopathy, Progressive Multifocal - diagnosis Leukoencephalopathy, Progressive Multifocal - drug therapy Leukoencephalopathy, Progressive Multifocal - mortality Magnetic Resonance Imaging Male Medical sciences Organophosphonates - therapeutic use Pharmacology. Drug treatments Survival Rate Viral diseases Viral diseases of the nervous system
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Zusammenfassung:	The prognosis of patients with progressive multifocal leukoencephalopathy (PML) has been reported to be poor even in the HAART era, with median survivals of 131-646 days in previous studies. We report a much longer median survival in all patients with confirmed PML presenting to our unit between 1998 and 2005.
ISSN:	0269-9370 1473-5571
DOI:	10.1097/01.aids.0000216390.83351.87