Bioassay-derived androgenic and estrogenic activity in municipal sewage in Australia and New Zealand

Raw sewage and sewage at various stages of treatment were sampled from 15 municipal sewage treatment plants in south Queensland (Australia) and Canterbury (New Zealand). Estrogenic and androgenic activities were determined with sheep estrogen receptor and rainbow trout androgen receptor binding assa...

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Veröffentlicht in:	Ecotoxicology and environmental safety 2006-11, Vol.65 (3), p.403-411
Hauptverfasser:	Leusch, Frédéric D.L., Chapman, Heather F., van den Heuvel, Michael R., Tan, Benjamin L.L., Gooneratne, S. Ravi, Tremblay, Louis A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens - metabolism Animal, plant and microbial ecology Animals Applied ecology Benzhydryl Compounds Binding, Competitive Biological and medical sciences Biological Assay Ecotoxicology, biological effects of pollution Environmental Monitoring Estradiol - analysis Estradiol - metabolism Estradiol equivalents (EEq) Estrogens, Non-Steroidal - analysis Estrogens, Non-Steroidal - metabolism Estrone - analysis Estrone - metabolism Fundamental and applied biological sciences. Psychology General aspects New Zealand Oncorhynchus mykiss Phenols - analysis Phenols - metabolism Queensland Receptor binding assay Receptors, Androgen - metabolism Receptors, Estrogen - metabolism Sewage - analysis Sheep Solid-phase extraction Testosterone equivalents (TEq) Waste Disposal, Fluid - methods Water Pollutants, Chemical - analysis Water Pollutants, Chemical - metabolism
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Beschreibung
Zusammenfassung:	Raw sewage and sewage at various stages of treatment were sampled from 15 municipal sewage treatment plants in south Queensland (Australia) and Canterbury (New Zealand). Estrogenic and androgenic activities were determined with sheep estrogen receptor and rainbow trout androgen receptor binding assays, respectively. Selected estrogenic chemicals were also analyzed by gas chromatography–mass spectrometry. The raw sewage influents contained significant levels of both estrogenic (
ISSN:	0147-6513 1090-2414
DOI:	10.1016/j.ecoenv.2005.07.020