Relationship between iron replacement and hepatic functions in hepatitis C virus-positive chronic haemodialysis patients

Aim: To investigate the effects of intravenous (i.v.) iron replacement on hepatic functions of hepatitis C virus (HCV)‐positive haemodialysis patients. Methods: The present retrospective study included 89 HCV‐positive and 57 HCV‐negative haemodialysis patients. Alanine aminotransferase (ALT) levels were accepted as sustained high if the last three values were ≥20 U/L. All patients and the HCV‐positive group were dichotomised into subgroups by the median for dialysis duration, the amounts of i.v. iron administered per year and totally. Results: Sustained high levels of ALT were significantly more frequent in the HCV‐positive group (P