TRPA1 receptor localisation in the human peripheral nervous system and functional studies in cultured human and rat sensory neurons

TRPA1 is a receptor expressed by sensory neurons, that is activated by low temperature (

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Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience letters 2008-06, Vol.438 (2), p.221-227
Hauptverfasser:	Anand, U., Otto, W.R., Facer, P., Zebda, N., Selmer, I., Gunthorpe, M.J., Chessell, I.P., Sinisi, M., Birch, R., Anand, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Animals Biological and medical sciences Calcium Channels - genetics Calcium Channels - metabolism Calcium Signaling - drug effects Calcium Signaling - physiology Cells, Cultured Child, Preschool DRG neurons Female Fundamental and applied biological sciences. Psychology Ganglia, Spinal - cytology Ganglia, Spinal - metabolism Human Humans Immunohistochemistry Irritants - pharmacology Male Middle Aged Nerve Nerve Growth Factors - pharmacology Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Neurons, Afferent - cytology Neurons, Afferent - metabolism Nociceptors - cytology Nociceptors - metabolism Pain Pain - metabolism Pain - physiopathology Peripheral Nervous System - cytology Peripheral Nervous System - metabolism Rats Rats, Wistar Rhizotomy Transient Receptor Potential Channels - genetics Transient Receptor Potential Channels - metabolism TRPA1 TRPA1 Cation Channel TRPV Cation Channels - metabolism Vertebrates: nervous system and sense organs
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Beschreibung
Zusammenfassung:	TRPA1 is a receptor expressed by sensory neurons, that is activated by low temperature (
ISSN:	0304-3940 1872-7972
DOI:	10.1016/j.neulet.2008.04.007