Urinary tract infection is common in VLBW infants

Objective Determine the significance of urinary tract infection (UTI) as a cause of late onset sepsis (LOS) in very low birth weight (VLBW) infants in the Neonatal Intensive Care Unit (NICU). Study design Analysis of blood, cerebrospinal fluid and urine culture results in VLBW infants >72-h old,...

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Veröffentlicht in:	Journal of perinatology 2019-01, Vol.39 (1), p.80-85
Hauptverfasser:	Drumm, Caitlin M., Siddiqui, Javedan N., Desale, Sameer, Ramasethu, Jayashree
Format:	Artikel
Sprache:	eng
Schlagworte:	692/420/254 692/699/255/1318 Anti-Bacterial Agents - administration & dosage Antibiotics Birth weight Blood Cerebrospinal fluid Complications and side effects Demographic aspects Design analysis Early Diagnosis Early Medical Intervention - methods Early Medical Intervention - standards Female Gram-Negative Bacteria - classification Gram-Negative Bacteria - isolation & purification Health aspects Humans Infant, Newborn Infant, Very Low Birth Weight - urine Infants Infections Intensive care Intensive Care Units, Neonatal - statistics & numerical data Intensive Care, Neonatal - methods Intensive Care, Neonatal - standards Low birth weight Male Medicine Medicine & Public Health Neonatal care Neonatal Sepsis - epidemiology Neonatal Sepsis - etiology Neonatal Sepsis - prevention & control Neonates Newborn infants Pediatric research Pediatric Surgery Pediatrics Risk factors Sepsis Statistics United States - epidemiology Urinalysis - methods Urinalysis - statistics & numerical data Urinary tract Urinary tract diseases Urinary tract infections Urinary Tract Infections - diagnosis Urinary Tract Infections - epidemiology Urinary Tract Infections - microbiology Urinary Tract Infections - therapy Urine Urogenital system Weight
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Zusammenfassung:	Objective Determine the significance of urinary tract infection (UTI) as a cause of late onset sepsis (LOS) in very low birth weight (VLBW) infants in the Neonatal Intensive Care Unit (NICU). Study design Analysis of blood, cerebrospinal fluid and urine culture results in VLBW infants >72-h old, admitted to the Georgetown University Hospital NICU between 2005 and 2015. Result Of 527 VLBW infants, 297 (56.4%) underwent 911 evaluations for LOS; only one-third included urine cultures. UTI was diagnosed in 8.5% of VLBW infants (range 2–15.9%) and in 13.8% of infants weighing
ISSN:	0743-8346 1476-5543
DOI:	10.1038/s41372-018-0226-4