Statewide Newborn Screening Program for Severe Combined Immunodeficiency (SCID) by Quantitating T-cell Receptor Excision Circles (TRECs)

Statewide Newborn Screening Program for Severe Combined Immunodeficiency (SCID) by Quantitating T-cell Receptor Excision Circles (TRECs)

Rationale The productive rearrangement of the T-cell receptor generates T-cell receptor excision circles (TRECs), which are present in naive T-cells.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of allergy and clinical immunology 2008-03, Vol.121 (3), p.798-798
Hauptverfasser: Grossman, W.J, Routes, J.M, Laessig, R.H, Baker, M.W
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Medical screening
T cell receptors
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Zusammenfassung:Rationale The productive rearrangement of the T-cell receptor generates T-cell receptor excision circles (TRECs), which are present in naive T-cells.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2008.01.066