Zytotoxizität der Extrakte von Schimmelpilzen aus feuchtebelasteten Gebäuden

Two toxicity tests (pollen tube growth test and methylen blue-assay) were examined regarding their sensitivity towards certain chosen mycotoxins. The IC50 values of the PTGT were in a concentration range between 0,01 μg/ml and 11,18 μg/ml, of the MB-assay in a concentration range between 0,003 μg/ml and 17,91 μg/ml. Both tests can be used to record toxigenic fungal wild strains in mould-infested apartments. Independently from the well-known immunochemical methods or HPLC/GC-MS analysis must be used for an exact determination of the kind and the content of the mycotoxins.